Monoclonal Anti-CACNB1 antibody produced in mouse
SIGMA/SAB5200033 - clone S7-18, 1 mg/mL, purified immunoglobulin
Synonym: Anti-CAB1; Anti-CACNB1; Anti-CACNLB1; Anti-Cavbeta1, S7-18; Anti-voltage dependent L type calcium channel beta 1 subunit
Product Type: Chemical
Immunoblotting Monoclonal Anti-CACNB1, Clone S7-18: Cat. No. SAB5200033: Western Blot analysis of CACNB1 in rat brain membrane extract using a 1:1,000 antibody dilution.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | S7-18, monoclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous glycerol solution |
| isotype | IgG1 |
| mol wt | antigen predicted mol wt 55 kDa |
| antigen predicted mol wt 80 kDa | |
| NCBI accession no. | NP_059042   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse, rat |
| storage temp. | −20°C |
| technique(s) | immunohistochemistry: suitable |
| immunoprecipitation (IP): suitable | |
| western blot: suitable | |
| UniProt accession no. | Q02641 |
| Biochem/physiol Actions: | The gene CACNB1 (calcium voltage-gated channel auxiliary subunit β 1) encodes the human brain β1 subunit of voltage dependent calcium channels called dihydropyridine receptors (DHPR). They detect changes in membrane voltage by activating ryanodine receptors to release Ca2+ from the sarcoplasmic reticulum into the cytosol, leading to excitation–contraction (EC) coupling. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | The gene CACNB1 (calcium voltage-gated channel auxiliary subunit β 1) encodes a member of the calcium channel β subunit family. The gene spanning a length of 25kb contains 13 exons and is mapped to human chromosome 17. Alternative splicing at exons 7 and 13 produces β1a,β1b and βlc isoforms. |
| Immunogen: | Synthetic peptide amino acids 19-34 of rat CavB1, Accession Number NP_059042 |
| Physical form: | Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide |
| Specificity: | Detects ~80, 55 kDa. No cross-reactivity against Cav Beta4 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |