Monoclonal Anti-ITPR1 antibody produced in mouse
SIGMA/SAB5200080 - clone S24-18, 1 mg/mL, purified immunoglobulin
Synonym: Anti-IP3 Receptor
Product Type: Chemical
Immunohistochemistry Monoclonal Anti-ITPR1, Clone S24-18: Cat. No. SAB5200080: Immunohistochemistry of ITPR1 on mouse cerebellum. Immunohistochemistry shows intense staining of giant neurons and axonal fibers.
Immunohistochemistry Monoclonal Anti-ITPR1, Clone S24-18: Cat. No. SAB5200080: Immunohistochemistry of ITPR1 on mouse cerebellum. Immunohistochemistry shows intense staining of giant neurons and axonal fibers.
Immunoblotting Monoclonal Anti-ITPR1, Clone S24-18: Cat. No. SAB5200080: Western Blot analysis of ITPR1 on rat brain membrane tissues using a 1:1,000 antibody dilution.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | S24-18, monoclonal |
| concentration | 1 mg/mL |
| conjugate | unconjugated |
| form | buffered aqueous glycerol solution |
| isotype | IgG1 |
| mol wt | antigen predicted mol wt 300 kDa |
| NCBI accession no. | NP_001007236.1   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | human, mouse, rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable |
| immunoprecipitation (IP): suitable | |
| western blot: suitable | |
| UniProt accession no. | Q14643 |
| Application: | Monoclonal Anti-ITPR1 antibody produced in mouse has been used for Western blotting. |
| Biochem/physiol Actions: | Detects ~300 kDa. Does not recognize type 2 or type 3 IP3R′s. |
| Biochem/physiol Actions: | Inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1) takes part in Ca2+ signaling on binding to its ligand, inositol 1,4,5-trisphosphate. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | Inositol 1,4,5-trisphosphate receptor, type 1 (ITPR1) is highly expressed in the rat brain and is also seen in the heart. It possesses an inositol-triphosphate binding domain, a channel-forming region and a regulatory region. ITPR1 is composed of 2749 amino acids. The gene ID for the protein is 25262. |
| Immunogen: | Fusion protein amino acids 2680-2749 (cytoplasmic carboxyl terminus) of rat type1 IP3R inositol 1,4,5-triphosphate receptor type 1, Itpr1 |
| Physical form: | Solution in PBS, pH 7.4, 50% glycerol, and 0.09% sodium azide |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |