Monoclonal Anti-Notch1 - Percp antibody produced in mouse
SIGMA/SAB5200921 - clone S253-32, purified immunoglobulin
Synonym: Anti-Motch; Anti-Neurogenic locus notch homolog protein 1; Anti-Neurogenic locus notch protein homolog; Anti-TAN1
Product Type: Product-on-demand
antibody form | purified immunoglobulin |
antibody product type | primary antibodies |
biological source | mouse |
clone | S253-32, monoclonal |
concentration | 1 mg/mL |
conjugate | Peridinin-Chlorophyll-Pro |
form | buffered aqueous solution |
isotype | IgG1 |
mol wt | antigen predicted mol wt >270, ~120 kDa |
NCBI accession no. | NP_032740.3 ![]() ![]() |
Quality Level | 100 ![]() |
shipped in | wet ice |
species reactivity | mouse, rat, human |
storage temp. | −20°C |
technique(s) | immunocytochemistry: suitable |
western blot: suitable | |
UniProt accession no. | Q07008 ![]() ![]() |
Biochem/physiol Actions: | The Notch signaling pathway regulates endothelial-cell differentiation, proliferation and apoptosis, and is essential for the development, maintenance and remodeling of the vascular system. Notch signaling pathway is involved in the development and progress of cardiovascular diseases. Notch1 function is predominant in developing kidney compared to compared to the mature organ. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. ![]() |
General description: | The NOTCH1 gene is mapped to human chromosome 9q34.3. In mice, Notch1 is highly expressed in immature neurons of hippocampus. Notch1 is localized to renal epithelial cells and podocytes of metanephros. |
Immunogen: | Fusion protein amino acids 20-216 (extracellular N-terminus, EGF-like domains 1-5) of mouse Notch1 |
Physical form: | PBS pH7.4, 50% glycerol, 0.09% sodium azide |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |