Monoclonal Anti-Lrrk2/Dardarin - Biotin antibody produced in mouse
SIGMA/SAB5201187 - clone S231B-34, purified immunoglobulin
Synonym: Anti-Dardarin; Anti-Leucine-rich repeat kinase 2; Anti-PARK8; Anti-RIP7
Product Type: Product-on-demand
antibody form | purified immunoglobulin |
antibody product type | primary antibodies |
biological source | mouse |
clone | S231B-34, monoclonal |
concentration | 1 mg/mL |
conjugate | biotin conjugate |
form | buffered aqueous solution |
isotype | IgG2a |
mol wt | antigen predicted mol wt 200 kDa |
NCBI accession no. | NP_940980 ![]() ![]() |
Quality Level | 100 ![]() |
shipped in | wet ice |
species reactivity | human, rat |
storage temp. | −20°C |
technique(s) | immunocytochemistry: suitable |
immunohistochemistry: suitable | |
western blot: suitable | |
UniProt accession no. | Q5S007 ![]() ![]() |
Biochem/physiol Actions: | Mutation in the leucine rich repeat kinase 2 (LRRK2) gene causes familial Parkinson′s disease (PD) and sporadic PD. Mitochondrial dysfunction is observed as a result of LRRK2 gene variation. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. ![]() |
General description: | Leucine rich repeat kinase 2 (LRRK2) is a large protein containing protein-protein interaction region enclosing two main domains for : central kinase and GTPase. |
Immunogen: | Fusion protein amino acids 841-960 of human LRRK2. 81% identical in mouse, 80% identical in rat. <30% identity with LRRK1. |
Physical form: | PBS pH 7.4, 50% glycerol, 0.1% sodium azide |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |