Monoclonal Anti-AIFM1 antibody produced in mouse
SIGMA/SAB5300151 - clone 4E7, ascites fluid
Synonym: AIF; AIFM1; COXPD6; MGC111425; PDCD8
Product Type: Product-on-demand
antibody form | ascites fluid |
antibody product type | primary antibodies |
biological source | mouse |
clone | 4E7, monoclonal |
conjugate | unconjugated |
isotype | IgG2b |
mol wt | 67 kDa |
NCBI accession no. | NM_001130846 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | mouse, monkey, human, rat |
storage temp. | −20°C |
technique(s) | direct ELISA: 1:10,000 |
flow cytometry: 1:200-1:400 | |
immunohistochemistry: 1:200-1:1,000 | |
indirect immunofluorescence: 1:200-1:1,000 | |
western blot: 1:500-1:2,000 |
Biochem/physiol Actions: | AIFM1 (apoptosis inducing factor mitochondria associated 1) possesses redox activity, which helps in oxidative phosphorylation. In the mitochondria, AIFM1 helps in assembling or maintaining the mitochondrial respiratory complexes I and III. It plays a vital role in apoptosis. This gene is associated with COXPD6 (combined oxidative phosphorylation deficiency, encephalomyopathy, Cowchock syndrome and X-linked deafness with neuropathy. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
General description: | AIFM1 (apoptosis inducing factor mitochondria associated 1) codes for apoptosis-inducing factor 1(AIF). It is located on human chromosome Xq26.1. AIF is a caspase-independent cell death effector. |
Immunogen: | Purified recombinant fragment of human AIF expressed in E.coli. Mouse monoclonal antibody raised against AIF |
Physical form: | Ascitic fluid containing 0.03% sodium azide. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |