Monoclonal Anti-RET antibody produced in mouse
SIGMA/SAB5300387 - clone 8D10C9, ascites fluid
Synonym: RET
Product Type: Product-on-demand
antibody form | ascites fluid |
antibody product type | primary antibodies |
biological source | mouse |
clone | 8D10C9, monoclonal |
conjugate | unconjugated |
isotype | IgG1 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | human |
storage temp. | −20°C |
target post-translational modification | unmodified |
technique(s) | direct ELISA: 1:10,000 |
western blot: 1:500-1:2,000 | |
UniProt accession no. | P07949 |
Biochem/physiol Actions: | The RET (rearranged during transfection) is involved in signal transduction pathways related to cell proliferation and differentiation. Mutations in RET gene results in medullary thyroid carcinoma and Hirschsprung′s disease. It is involved in normal development and cancer. The isoforms of RET provides distinct protein complexes to promote signals. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
General description: | The RET (rearranged during transfection) proto-oncogene is mapped to human chromosome 10q11. It has two isoforms, namely RET9 and RET51 with unique C-terminal tail sequences. RET is made of 20 exons and 21 introns. |
Immunogen: | Purified recombinant fragment of RET (aa896-1063) expressed in E.coli. Mouse monoclonal antibody raised against RET |
Physical form: | Ascitic fluid containing 0.03% sodium azide. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |