Monoclonal Anti-PTK2B antibody produced in mouse
SIGMA/SAB5300394 - clone 5E2D5, ascites fluid
Synonym: CAKB; FAK2; FRNK; PKB; PTK
Product Type: Product-on-demand
antibody form | ascites fluid |
antibody product type | primary antibodies |
biological source | mouse |
clone | 5E2D5, monoclonal |
conjugate | unconjugated |
isotype | IgG2a |
mol wt | 115.8 kDa |
NCBI accession no. | NM_173174 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | human |
storage temp. | −20°C |
technique(s) | direct ELISA: 1:10,000 |
immunohistochemistry: 1:200-1:1,000 | |
western blot: 1:500-1:2,000 |
Biochem/physiol Actions: | Protein tyrosine kinase 2 β (PTK2B) takes part in the β2-mediated signaling pathway and activates mitogen activated protein kinase pathway. The protein has been shown to be upregulated in many tumors. PTK2B also has a role in cell proliferation and migration. It regulates ion channels which are induced by calcium. |
Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
General description: | Protein tyrosine kinase 2 β (PTK2B) is a member of the focal adhesion kinase family which is expressed in the brain. The gene encoding it is localized on human chromosome 8. |
Immunogen: | Purified recombinant fragment of PYK2 (aa815-997) expressed in E.coli. Mouse monoclonal antibody raised against PYK2 |
Physical form: | Ascitic fluid containing 0.03% sodium azide. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |