Anti-COX2 antibody, Rabbit monoclonal
SIGMA/SAB5500087 - clone SP21, recombinant, expressed in proprietary host, tissue culture supernatant
Product Type: Product-on-demand
Immunohistochemistry Anti-COX2: Cat. No. SAB5500087: Immunohistochemistry of COX-2 in Human colon carcinoma tissue with COX-2 antibody.
| antibody form | tissue culture supernatant |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | SP21, monoclonal |
| conjugate | unconjugated |
| isotype | IgG |
| Quality Level | 100  |
| recombinant | expressed in proprietary host |
| shipped in | wet ice |
| species reactivity | human (tested) |
| species reactivity (predicted by homology) | mouse, frog, bovine, rat, dog |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: 1:100 |
| UniProt accession no. | P35354  |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | COX-2 (Cyclooxygenase-2) is an inducible enzyme. It is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression. Given its role in synthesizing prostaglandins, COX-2 is therefore of interest in studying immune response regulation. COX-2 is induced by a wide variety of stimuli and was initially identified as immediate-early growth response gene. In addition, COX-2 expression markedly increased in 85-90% of human colorectal adenocarcinoma whereas COX-1 levels remain unchanged. |
| Immunogen: | Synthetic peptide corresponding to C-terminus of rat COX-2. |
| Physical form: | 0.1 ml rabbit monoclonal antibody supplied as tissue culture supernatant in TBS/1% BSA buffer pH 7.5 with less than 0.1% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |