Anti-EGFR antibody, Rabbit monoclonal
SIGMA/SAB5500098 - recombinant, expressed in proprietary host, clone SP111, affinity isolated antibody
Product Type: Product-on-demand
Immunohistochemistry Anti-EGFR (E746-A750del): Cat. No. SAB5500098: Immunohistochemistry of Epidermal Growth Factor Receptor (EGFR) (E746-A750del) in Human lung carcinoma with E746-A750 deletion tissue with Epidermal Growth Factor Receptor (EGFR) (E746-A750del) antibody.
Immunoblotting Anti-EGFR (E746-A750del): Cat. No. SAB5500098: Immunoblotting analysis of Epidermal Growth Factor Receptor (EGFR) (E746-A750del) in HCC827 cell lysate with Epidermal Growth Factor Receptor (EGFR) (E746-A750del) antibody.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | SP111, monoclonal |
| conjugate | unconjugated |
| isotype | IgG |
| Quality Level | 100  |
| recombinant | expressed in proprietary host |
| shipped in | wet ice |
| species reactivity | human (tested) |
| storage temp. | 2-8°C |
| technique(s) | immunoblotting: 1:300 |
| immunohistochemistry: 1:100 | |
| UniProt accession no. | P00533  |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | EGFR is a transmembrane tyrosine kinase that belongs to the HER/erbB protein family. Somatic mutations in the tyrosine kinase domain of EGFR are present in a subset of lung adenocarcinoma. Two types of mutations account for approximately 90% of mutant cases: a specific point mutation L858R which occurs in exon 21 and short in-frame deletions in exon 19. A common lesion in exon 19 is the deletion of E746-A750, although other variants can also occur. |
| Immunogen: | E746-A750del specific |
| Physical form: | 0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |