Anti-Phospho-AMPA Receptor antibody, GluR 1 subunit (Ser845), Rabbit Monoclonal
SIGMA/SAB5600106 - recombinant, expressed in HEK 293 cells, clone RM296, purified immunoglobulin
Synonym: Glutamate Receptor 1
Product Type: Chemical
Immunohistochemistry Immunohistochemical staining of formalin fixed and paraffin embedded Human brain tissue section using Anti-Phospho-AMPA Receptor (GluR 1) (Ser845) Rabbit monoclonal antibody (clone RM296) at a 1:200 dilution.
Western Blotting Western Blot of Mouse brain tissue lysate, non-treated (-) or dephosphorylated (+) with Lambda Protein Phosphatase (lPP), using Anti-Phospho-AMPA Receptor (GluR 1) (Ser845) Rabbit monoclonal antibody (clone RM296) at a 1:200 dilution.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | recombinant monoclonal |
| RM296, monoclonal | |
| form | buffered aqueous glycerol solution |
| isotype | IgG |
| NCBI accession no. | 2890   |
| Quality Level | 100 |
| recombinant | expressed in HEK 293 cells |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pSer845) |
| technique(s) | immunohistochemistry: 1:100-1:200 |
| western blot: 1:100-1:200 |
| Biochem/physiol Actions: | GLUR1/GRIA1 (glutamate ionotropic receptor AMPA type subunit 1) plays an important role in long-term potentiation (LTP). It is associated with migraine. |
| Biochem/physiol Actions: | This antibody reacts to human Glutamate Receptor 1, AMPA Receptor (GluR1) only when phosphorylated at Ser845. There is no cross-reactivity to GluR1 that is not phosphorylated at Ser845. This antibody may also react to mouse or rat Phospho-AMPA Receptor (GluR1) (Ser845) as predicted by immunogen homology. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | GLUR1/GRIA1 (glutamate ionotropic receptor AMPA type subunit 1) is located on human chromosome 5q33.2. It is expressed mainly in brain areas. |
| Immunogen: | A phospho-peptide corresponding to human Phospho-Glutamate Receptor 1 (GluR1) (Ser845). |
| Physical form: | Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |