Anti-CD140b (PDGF Receptor beta)antibody, Rabbit Monoclonal
SIGMA/SAB5600114 - recombinant, expressed in HEK 293 cells, clone RM303, purified immunoglobulin
Synonym: Platelet-derived growth factor receptor beta
Product Type: Chemical
Immunohistochemistry
Immunohistochemical staining of formalin fixed and paraffin embedded Human kidney tissue section using Anti-CD140b Rabbit monoclonal antibody (Clone RM303) at a 1:1000 dilution.
Immunohistochemical staining of formalin fixed and paraffin embedded Human kidney tissue section using Anti-CD140b Rabbit monoclonal antibody (Clone RM303) at a 1:1000 dilution.
Western Blotting
Western Blot of Human brain tissue lysate using Anti-CD140b Rabbit monoclonal antibody (Clone RM303) at a 1:250 dilution.
Western Blot of Human brain tissue lysate using Anti-CD140b Rabbit monoclonal antibody (Clone RM303) at a 1:250 dilution.
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | recombinant monoclonal |
| RM303, monoclonal | |
| conjugate | unconjugated |
| form | buffered aqueous glycerol solution |
| isotype | IgG |
| NCBI accession no. | 5159   |
| Quality Level | 100 |
| recombinant | expressed in HEK 293 cells |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: 1:500-1:1000 |
| western blot: 1:250-1:500 |
| Biochem/physiol Actions: | PDGFRB (platelet derived growth factor receptor β) acts as a regulator of mesenchymal cells in tumour cells. Upregulation of the gene is observed in gastric cancer, breast and prostate cancers. Mutations in the gene is associated with infantile myofibromatosis. |
| Biochem/physiol Actions: | This antibody reacts to human CD140b (PDGFR-beta) (Platelet-derived growth factor receptor beta). |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Features and Benefits: | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| General description: | The PDGFRB (platelet derived growth factor receptor β) gene is mapped to human chromosome 5q32. It encodes for a receptor tyrosine kinase. |
| Immunogen: | A peptide corresponding to the C-terminus of human CD140b. |
| Physical form: | Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |