Anti-NBN antibody produced in rabbit
SIGMA/SAB5700013
Synonym: AT-V1; AT-V2; ATV; NBN; NBS; NBS1; P95; nibrin
Product Type: Chemical
antibody form | affinity isolated antibody |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.96 mg/ml |
form | buffered aqueous solution |
mol wt | 84 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | human, mouse |
storage temp. | −20°C |
technique(s) | western blot: 1:500-1:2000 |
UniProt accession no. | O60934 |
General description: | Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 435-754 of human NBN (NP_002476.2). |
Physical form: | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage and Stability: | Store at -20℃. Avoid freeze / thaw cycles. |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |