Anti-RB antibody produced in rabbit
SIGMA/SAB5700023
Synonym: OSRC; PPP1R130; RB; RB1; Rb; p105-Rb; pRb; pp110
Product Type: Chemical
antibody form | affinity isolated antibody |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.72 mg/ml |
form | buffered aqueous solution |
mol wt | 106 |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | human, rat |
storage temp. | −20°C |
technique(s) | immunofluorescence: 1:50-1:100 |
immunohistochemistry: 1:50-1:100 | |
western blot: 1:500-1:2000 | |
UniProt accession no. | P06400 |
General description: | The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
Immunogen: | Recombinant protein of human RB1. |
Physical form: | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage and Stability: | Store at -20℃. Avoid freeze / thaw cycles. |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |