Anti-MAPK9 antibody produced in rabbit
SIGMA/SAB5700080
Synonym: JNK-55; JNK2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; MAPK9; PRKM9; SAPK; SAPK1a; p54a; p54aSAPK
Product Type: Chemical
antibody form | affinity isolated antibody |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.83 mg/ml |
form | buffered aqueous solution |
mol wt | 27 |
44 | |
48 | |
Quality Level | 100 |
shipped in | wet ice |
species reactivity | human, mouse |
storage temp. | −20°C |
technique(s) | immunofluorescence: 1:50-1:200 |
immunohistochemistry: 1:50-1:200 | |
western blot: 1:500-1:2000 | |
UniProt accession no. | P45984 |
General description: | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene′s mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-424 of human MAPK9 (NP_002743.3). |
Physical form: | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage and Stability: | Store at -20℃. Avoid freeze / thaw cycles. |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |