Anti-Phospho-EIF4G1-S1108 antibody produced in rabbit
SIGMA/SAB5700464
Synonym: EIF-4G1; EIF4F; EIF4G; EIF4G1; EIF4GI; P220; PARK18
Product Type: Chemical
antibody form | affinity isolated antibody |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.52mg/ml |
form | buffered aqueous solution |
mol wt | 154 |
158 | |
166 | |
171 | |
175 | |
176 | |
Quality Level | 100 ![]() |
shipped in | wet ice |
species reactivity | rat, mouse, human |
storage temp. | −20°C |
technique(s) | western blot: 1:500-1:2000 |
UniProt accession no. | Q04637 ![]() ![]() |
General description: | The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5′-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. |
Immunogen: | A synthetic phosphorylated peptide around S1108 of human EIF4G1 (NP_001181875.1). |
Physical form: | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage and Stability: | Store at -20℃. Avoid freeze / thaw cycles. |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |