Anti-DDIT3/CHOP antibody produced in rabbit
SIGMA/SAB5700602
Synonym: C/EBPzeta; CEBPZ; CHOP; CHOP-10; CHOP10; DDIT3; DDIT3 / CHOP; GADD153
Product Type: Chemical
antibody form | affinity isolated antibody |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 4.62 mg/ml |
form | buffered aqueous solution |
mol wt | 19 |
21 | |
Quality Level | 100 ![]() |
shipped in | wet ice |
species reactivity | human, rat, mouse |
storage temp. | −20°C |
technique(s) | immunofluorescence: 1:50-1:200 |
immunohistochemistry: 1:50-1:200 | |
western blot: 1:500-1:2000 | |
UniProt accession no. | P35638 ![]() ![]() |
General description: | This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human DDIT3 / CHOP (NP_004074.2). |
Physical form: | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage and Stability: | Store at -20℃. Avoid freeze / thaw cycles. |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |