Anti-IGF1R antibody produced in rabbit
SIGMA/SAB5700614
Synonym: CD221; IGF1R; IGFIR; IGFR; JTK13
Product Type: Chemical
antibody form | affinity isolated antibody |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 2.5 mg/ml |
form | buffered aqueous solution |
mol wt | 154 |
Quality Level | 100 ![]() |
shipped in | wet ice |
species reactivity | human, mouse, rat |
storage temp. | −20°C |
technique(s) | immunofluorescence: 1:50-1:200 |
immunohistochemistry: 1:50-1:200 | |
western blot: 1:500-1:2000 | |
UniProt accession no. | P08069 ![]() ![]() |
General description: | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 660-760 of human IGF1R (NP_000866.1). |
Physical form: | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage and Stability: | Store at -20℃. Avoid freeze / thaw cycles. |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |