Anti-NEFL antibody produced in rabbit
SIGMA/SAB5700619
Synonym: CMT1F; CMT2E; NEFL; NF-L; NF68; NFL; PPP1R110
Product Type: Chemical
antibody form | affinity isolated antibody |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 1.13mg/ml |
form | buffered aqueous solution |
mol wt | 61 |
Quality Level | 100 ![]() |
shipped in | wet ice |
species reactivity | rat, human, mouse |
storage temp. | −20°C |
technique(s) | immunofluorescence: 1:50-1:200 |
immunohistochemistry: 1:50-1:200 | |
western blot: 1:500-1:2000 | |
UniProt accession no. | P07196 ![]() ![]() |
General description: | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 400-543 of human NEFL (NP_006149.2). |
Physical form: | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage and Stability: | Store at -20℃. Avoid freeze / thaw cycles. |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |