Anti-p38 MAPK antibody produced in rabbit
SIGMA/SAB5700685
Synonym: CSBP; CSBP1; CSBP2; CSPB1; EXIP; MAPK14; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38 MAPK; p38ALPHA
Product Type: Chemical
antibody form | affinity isolated antibody |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 1.91 mg/ml |
form | buffered aqueous solution |
mol wt | 29 |
34 | |
35 | |
41 | |
Quality Level | 100 ![]() |
shipped in | wet ice |
species reactivity | rat, human, mouse |
storage temp. | −20°C |
technique(s) | western blot: 1:500-1:2000 |
UniProt accession no. | Q16539 ![]() ![]() |
General description: | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-360 of human p38 MAPK (NP_620581.1). |
Physical form: | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage and Stability: | Store at -20℃. Avoid freeze / thaw cycles. |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |