Anti-c-Myc antibody produced in rabbit
SIGMA/SAB5700727
Synonym: MRTL; MYC; MYCC; bHLHe39; c-Myc
Product Type: Chemical
antibody form | affinity isolated antibody |
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 1.03 mg/ml |
form | buffered aqueous solution |
mol wt | 48 |
50 | |
Quality Level | 100 ![]() |
shipped in | wet ice |
species reactivity | mouse, human, rat |
storage temp. | −20°C |
technique(s) | western blot: 1:500-1:2000 |
UniProt accession no. | P01106 ![]() ![]() |
General description: | The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt′s lymphomas, suggesting its importance in the normal function of this gene. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human c-Myc (NP_002458.2). |
Physical form: | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage and Stability: | Store at -20℃. Avoid freeze / thaw cycles. |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352203 |