Anti-CD86 antibody produced in rabbit
SIGMA/SAB5701086
Product Type: Chemical
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 2.4 mg/mL |
form | liquid |
Quality Level | 100 ![]() |
shipped in | wet ice |
species reactivity | human, rat, mouse |
storage temp. | −20°C |
technique(s) | immunohistochemistry: 1:50-1:200 |
western blot: 1:500-1:2000 | |
UniProt accession no. | P42081 ![]() ![]() |
General description: | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. |
Immunogen: | Recombinant protein of human CD86. |
Physical form: | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage Temp. | −20°C |