Anti-Phospho-CGAS-S291 antibody produced in rabbit
SIGMA/SAB5701930
Product Type: Chemical
antibody product type | primary antibodies |
biological source | rabbit |
clone | polyclonal |
concentration | 0.439 mg/mL |
form | liquid |
Quality Level | 100 ![]() |
shipped in | wet ice |
species reactivity | rat, human |
storage temp. | −20°C |
technique(s) | western blot: 1:500-1:2000 |
UniProt accession no. | Q8C6L5 ![]() ![]() |
General description: | The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
Immunogen: | A phospho synthetic peptide corresponding to residues surrounding S291 of Mouse CGAS. |
Physical form: | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Storage Temp. | −20°C |