Kynurenine 3-Monooxygenase, Pseudomonas fluorescens (strain 17400), Recombinant
SIGMA/SAE0004
Synonym: KMO
Product Type: Chemical
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| form | solution |
| mol wt | 50,712 Da |
| Quality Level | 200  |
| shipped in | dry ice |
| specific activity | ≥3 U/mg |
| storage temp. | −70°C |
| General description: | Kynurenine 3-monooxygenase (KMO) is a flavoprotein aromatic hydroxylase (FAH) that catalyzes the hydroxylation of L-kynurenine (L-Kyn) to produce 3-hydroxykynurenine (3-OH-Kyn). This activity is central to tryptophan metabolism and also to the production of nicotinamide adenine dinucleotide (NAD) in higher organisms. KMO contains flavin adenine dinucleotide (FAD) as a non-covalent, but tightly bound, co-factor at a 1:1 ratio of co-factor to protein. |
| Other Notes: | 1 unit will oxidize L-kynurenine at 1 mol/min at pH 7.0, 25°C. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| activity | specific activity: ≥3 U/mg |
| Storage Temp. | −70°C |
| Enzyme Commission (EC) Number | 1.14.13.9 ( BRENDA  | IUBMB ) |
| UNSPSC | 12352204 |