NMQ/N-methyl-quinidine - MDR1/P-gp Substrate
SIGMA/SBNMQ
Synonym: SB-NMQ; N-methyl-quinidine (NMQ); NMQ
CAS Number: 42982-87-6
Empirical Formula (Hill Notation): C21H27IN2O2
Molecular Weight: 466.36
Linear Formula: C21H27IN2O2
Product Type: Chemical
color | white |
form | powder |
InChI | 1S/C21H27N2O2.HI/c1-4-14- |
InChI key | AJQSDVGBERUTGX-QVEQJUGRSA |
storage temp. | room temp |
Application: | NMQ/N-methyl-quinidine - MDR1/P-gp substrate has been used as a probe substrate for multidrug resistance protein 1 (MDR1) in vesicles assay. |
Biochem/physiol Actions: | SOLVO Biotechnology offers NMQ as a selective substrate for the MDR1 membrane transporter. NMQ was shown to be actively transported by human MDR1/P-gp and rat Mdr1b efflux transporters. |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H302 |
Hazard Codes | Xn |
Risk Statements | 22 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | room temp |
UNSPSC | 12352200 |