Daptomycin Ready Made Solution
SIGMA/SBR00014 - 1 mg/mL in DMSO
Synonym: N-
CAS Number: 103060-53-3
Empirical Formula (Hill Notation): C72H101N17O26
Molecular Weight: 1620.67
MDL Number: MFCD28968054
Linear Formula: C72H101N17O26
Product Type: Chemical
antibiotic activity spectrum | Gram-positive bacteria |
biological source | Streptomyces roseosporus |
color | colorless to faint yellow |
concentration | 1 mg/mL in DMSO |
description | Ready Made Solution |
form | liquid |
InChI | 1S/C72H101N17O26/c1-5-6-7 |
InChI key | DOAKLVKFURWEDJ-OFNKPWESSA |
mode of action | DNA synthesis | interferes |
protein synthesis | interferes | |
Quality Level | 200 ![]() |
shipped in | dry ice |
SMILES string | O=C(NCC(N[C@H](CCCN)C(N[C |
storage condition | (Keep container tightly closed in a dry and well-ventilated place.) |
storage temp. | −20°C |
Biochem/physiol Actions: | Daptomycin is a natural cyclic lipopeptide antibiotic found in Streptomyces roseosporus. It is has been found to be effective in treating infections caused by aerobic Gram-positive bacteria. Daptomycin inhibits many antibiotic resistant strains such as methicillin-resistant S. aureus (MRSA), vancomycin-intermediate S. aureus (VISA) and vancomycin-resistant S. aureus (VRSA). The mode of action of daptomycin is quite different from that of any other antibiotic. Daptomycin binds to bacterial membranes and causes a rapid depolarization of membrane potential. This loss of membrane potential causes inhibition of protein, DNA, and RNA synthesis, which results in bacterial cell death. |
Other Notes: | Keep container tightly closed in a dry and well-ventilated place. |
Packaging: | 0.5ML |
Preparation Note: | The 1 mg/mL solution may be further diluted in an appropriate buffer prior to use. It is recommended that a fresh dilution be made on the day of use. |
WGK Germany | WGK 1 |
Flash Point(F) | 188.6 °F |
Flash Point(C) | 87 °C |
Storage Temp. | −20°C |
UNSPSC | 12352200 |