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γ Secretase Inhibitor

SIGMA/SCP0004 - ≥95% (HPLC)

Empirical Formula (Hill Notation): C26H41N3O5
Molecular Weight: 475.62
Linear Formula: C26H41N3O5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SCP0004-5MG 5 mg
 $295.00
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This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

assay ≥95% (HPLC)
composition Peptide Content, ≥85%
form lyophilized
storage condition protect from light
storage temp. −20°C
Amino Acid Sequence: Z-Leu-Leu-Nle-al
Application: γ Secretase Inhibitor has been used to study the suppressive miR-129 functions through inhibition on estrogen receptor 1 (ESR1) and NOTCH signaling in breast cancer stem cells.
General description: Gamma-secretase is a protein complex containing presenilin, nicastrin, APH-1, and PEN-2. The leupeptin analogue Z-Leu-Leu-Nle-al (N-benzyloxycarbonyl-Leu-Leu-norleucinal; Benzyloxicarbonyl-Leu-Leu-Nle-CHO (LLNle)) and closely related peptides are used as protease and a gamma secretase inhibitors.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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