Amyloid Blocker
SIGMA/SCP0017
Empirical Formula (Hill Notation): C42H63N9O8
Molecular Weight: 822.01
Linear Formula: C42H63N9O8
Product Type: Chemical
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| assay | ≥95% (HPLC) |
| composition | Peptide Content, ≥75% |
| form | lyophilized |
| storage condition | protect from light |
| storage temp. | −20°C |
| Amino Acid Sequence: | Ac-Gln-Lys-Leu-Val-Phe-Ph |
| General description: | Amyloid plaques characteristic of the Alzheimer brain contain fibrils composed of amyloid β aggregates. Peptides, small organic molecules and nanoparticles can be used to bind or aggregate amyloid β (Aβ). They have been used as a strategy for the development of pharmaceutical approaches or agents to treat Alzheimer′s disease (AD). Short peptides containing the sequence KLVFF have been shown to bind specifically to the homologous region in Aβ and are used to prevent full length amyloid fibril formation. |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |