Caspase Inhibitor
SIGMA/SCP0095 - ≥95% (HPLC)
Synonym: Ac-LEHD-CHO; caspase 9 inhibitor
Empirical Formula (Hill Notation): C23H34N6O9
Molecular Weight: 538.55
Linear Formula: C23H34N6O9
Product Type: Chemical
| assay | ≥95% (HPLC) |
| composition | Peptide Content, ≥80% |
| form | lyophilized |
| storage condition | protect from light |
| storage temp. | −20°C |
| Amino Acid Sequence: | Ac-Leu-Glu-His-Asp-al |
| Biochem/physiol Actions: | Ac-Leu-Glu-His-Asp-al, or Ac-LEHD-CHO, is a cell-permeable tetrapeptide aldehyde. It is an inhibitor of caspase-9. Its target of action has been proposed to be the mitochondrial pathway of apoptosis. Ac-LEHD-CHO has also been postulated to prevent cleavage of caspase-8, and partly to prevent cleavage of caspase-3. |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |
