Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP)
SIGMA/SCP0157
Empirical Formula (Hill Notation): C22H37N9O10
Molecular Weight: 587.58
Linear Formula: C22H37N9O10
Product Type: Chemical
assay | ≥95% (HPLC) |
composition | Peptide Content, ≥60% |
form | lyophilized |
storage condition | protect from light |
storage temp. | −20°C |
Amino Acid Sequence: | Gly-Arg-Gly-Asp-Ser-Pro |
Application: | Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) has been used: • in coating well plate to monitor cell attachment by crystal violet staining • to treat baby hamster kidney (BHK-21) cells to study the role of Arg-Gly-Asp (RGD) motif in the replication of Japanese encephalitis virus (JEV) • to block RGD-dependent integrins or integrin signaling in INA-6 cells • to study the role of the RGD-binding integrins in Gal-3-mediated cell adhesion |
Biochem/physiol Actions: | Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) can stimulate endothelialization by modifying the surface of cardiovascular implants. The major cell- binding domain of GRGDSP helps to promote cell adhesion on a wide range of substrates. |
Biochem/physiol Actions: | Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide. GRGDSP is used widely together with other RGD peptides in integrin research. |
General description: | Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is a bioactive molecule/peptide derived from fibronectin. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352209 |