Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP)
SIGMA/SCP0157
Synonym: GRGDSP Peptide; RGD Peptide
Empirical Formula (Hill Notation): C22H37N9O10
Molecular Weight: 587.58
Linear Formula: C22H37N9O10
Product Type: Chemical
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| assay | ≥95% (HPLC) |
| composition | Peptide Content, ≥60% |
| form | lyophilized |
| storage condition | protect from light |
| storage temp. | −20°C |
| Amino Acid Sequence: | Gly-Arg-Gly-Asp-Ser-Pro |
| Application: | Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) has been used: • in coating well plate to monitor cell attachment by crystal violet staining • to treat baby hamster kidney (BHK-21) cells to study the role of Arg-Gly-Asp (RGD) motif in the replication of Japanese encephalitis virus (JEV) • to block RGD-dependent integrins or integrin signaling in INA-6 cells • to study the role of the RGD-binding integrins in Gal-3-mediated cell adhesion |
| Biochem/physiol Actions: | Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) can stimulate endothelialization by modifying the surface of cardiovascular implants. The major cell- binding domain of GRGDSP helps to promote cell adhesion on a wide range of substrates. |
| Biochem/physiol Actions: | Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide. GRGDSP is used widely together with other RGD peptides in integrin research. |
| General description: | Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is a bioactive molecule/peptide derived from fibronectin. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352209 |