Myosin Light Chain Kinase Substrate (smooth muscle)
SIGMA/SCP0196
Empirical Formula (Hill Notation): C61H107N23O16
Molecular Weight: 1418.65
Linear Formula: C61H107N23O16
Product Type: Chemical
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| assay | ≥95% (HPLC) |
| composition | Peptide Content, ≥62% |
| form | lyophilized |
| storage condition | protect from light |
| storage temp. | −20°C |
| Amino Acid Sequence: | Lys-Lys-Arg-Ala-Ala-Arg-A |
| Application: | Myosin Light Chain Kinase Substrate (smooth muscle) has been used in MLCK activity assay to study the role of Plasmodium falciparum calmodulin (Pf CaM). |
| Biochem/physiol Actions: | KKRAARATSNVFA-NH2 is used as a myosin light chain kinase (MLCK) substrate. |
| Biochem/physiol Actions: | Myosin light chain kinase (MLCK) is involved in modulating the actin-myosin interaction of smooth muscle. In addition to its kinase activity, MLCK also has actin-binding activity, which can assemble actin filaments into bundles. It also has myosin-binding activity, which can generate myosin filaments. |
| General description: | Myosin light chain kinase (MLCK) comprises an N-terminal actin-binding domain, a central kinase domain, and a C-terminal myosin-binding domain. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |