Prostate Specific Antigen Substrate
SIGMA/SCP0224
Synonym: KLK3; Kallikrein-related peptidase-3; PSA
Empirical Formula (Hill Notation): C44H64N12O13
Molecular Weight: 969.05
Linear Formula: C44H64N12O13
Product Type: Chemical
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| assay | ≥95% (HPLC) |
| composition | Peptide Content, ≥75% |
| form | lyophilized |
| storage condition | protect from light |
| storage temp. | −20°C |
| Amino Acid Sequence: | Mu-His-Ser-Ser-Lys-Leu-Gl |
| Application: | Prostate Specific Antigen Substrate has been used to assay recombinant severe acute respiratory syndrome coronavirus-2 viral 3-chymotrypsin-like cysteine protease (SARS-CoV-2 3CLpro). |
| Biochem/physiol Actions: | Prostate specific antigen (PSA). It exhibits chymotrypsin-like activity. PSA is the most abundant protease found in the prostate and secreted into the seminal fluid. It is a useful biomarker for prostate cancer. PSA digests the gel-forming proteins semenogelins I and II in semen. It shows antiangiogenic activity in vitro and in vivo. |
| General description: | Prostate specific antigen (PSA) is a kallikrein-related serine peptidase that belongs to the chymotrypsin subfamily serine protease. It was originally found in human semen. PSA is also detected in serum correlated to benign and metastatic disease. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352204 |