PAR-1 Selective Agonist
SIGMA/SCP0237 - ≥95% (HPLC)
CAS Number: 189388-22-5
Empirical Formula (Hill Notation): C31H53N9O6
Molecular Weight: 647.81
Linear Formula: C31H53N9O6
Product Type: Chemical
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| assay | ≥95% (HPLC) |
| composition | Peptide Content, ≥65% |
| form | lyophilized |
| storage condition | protect from light |
| storage temp. | −20°C |
| Amino Acid Sequence: | Thr-Phe-Leu-Leu-Arg-NH2 |
| Application: | PAR-1 selective agonist has been used for platelet aggregation. |
| Application: | Thr-Phe-Leu-Leu-Arg-NH2 (TFLLR-NH2) is used as a selective agonist for protease-activated receptor 1 (PAR1) which is involved in the development of cardiac remodeling and hypertrophy after myocardial injury. |
| Biochem/physiol Actions: | Protease-activated receptor-1 (PAR-1) is a G protein-coupled receptor, that is activated through thrombin and other proteases. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |