Arctiin
SIGMA/SMB00078 - ≥95% (LC/MS-ELSD)
Synonym: Arctigenin-
CAS Number: 20362-31-6
Empirical Formula (Hill Notation): C27H34O11
Molecular Weight: 534.55
MDL Number: MFCD00870630
Linear Formula: C27H34O11
Product Type: Chemical
| application(s) | metabolomics vitamins, nutraceuticals, and natural products |
| assay | ≥95% (LC/MS-ELSD) |
| form | solid |
| InChI | 1S/C27H34O11/c1-33-18-6-4 |
| InChI key | XOJVHLIYNSOZOO-SWOBOCGESA |
| SMILES string | COc1ccc(C[C@H]2COC(=O)[C@ |
| storage temp. | −20°C |
| Biochem/physiol Actions: | Arctiin has shown to be a suppressor of cyclin D1 protein expression in multiple types of human tumor cells, such as osteosarcoma, lung, colorectal, cervical, breast, melanoma, and prostate cancer. Arctiin has also shown antiviral activity against influenza A when used alone or in combination with oseltamivir. Arctiin plays an important role in the process of inflammation, by preventing the release of nitric oxide, prostaglandin E2, TNF-α (tumor necrosis factor − α), interleukin (IL)-1β and IL-6. A study using rat model shows that arctiin possess anti-diabetic activity and might serve as an inhibitor of diabetic retinopathy. |
| Biochem/physiol Actions: | Arctiin has shown to be a suppressor of cyclin D1 protein expression in multiple types of human tumor cells, such as osteosarcoma, lung, colorectal, cervical, breast, melanoma, and prostate cancer. Arctiin has also shown antiviral activity against influenza A when used along or in combination with oseltamivir. |
| General description: | Natural product derived from plant source, such as Forsythiae Fructus and Arctium lappa L. Arctiin is a lignan. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (LC/MS-ELSD) |
| Storage Temp. | −20°C |
| UNSPSC | 12352205 |