Dehydroabietic acid
SIGMA/SMB00089 - ≥90% (LC/MS-ELSD)
Synonym: Abieta-
CAS Number: 1740-19-8
Empirical Formula (Hill Notation): C20H28O2
Molecular Weight: 300.44
EC Number: 217-102-8
MDL Number: MFCD09839012
Linear Formula: C20H28O2
Product Type: Chemical
| application(s) | metabolomics vitamins, nutraceuticals, and natural products |
| assay | ≥90% (LC/MS-ELSD) |
| form | solid |
| InChI | 1S/C20H28O2/c1-13(2)14-6- |
| InChI key | NFWKVWVWBFBAOV-MISYRCLQSA |
| SMILES string | CC(C)c1ccc2c(CC[C@H]3[C@@ |
| storage temp. | −20°C |
| Application: | Dehydroabietic acid has been used as a reference standard: • to study the aging process of Pinus resins using Fourier-transform infrared spectroscopy (FTIR) • to study the composition changes in Pinus genus with aging using Raman spectroscopy complemented with infrared spectroscopy • to estimate resistance against biotic stress as proxy in chemical defenses in Pinus halepensis |
| Biochem/physiol Actions: | Dehydroabietic acid (DHA) exerts various biological activities such as anti-cancer, anti-aging, antimicrobial, antiulcer, gastroprotective, and cytotoxic activities. It is a potent anti-inflammatory agent and a dual activator of peroxisome proliferator-activated receptors alpha and gamma (PPAR α/γ). DHA has an anti-aging effect and a sirtuin 1 (SIRT1) activating compound. It has antibacterial properties against multidrug-resistant strains. dehydroabietic acid and its derivatives have gastroprotective and cytotoxic effects. |
| General description: | Dehydroabietic acid (DHA or DAA) is a bioactive phytochemical, diterpenoid found in various Pinus species. It is a resin acid and a derivative of abietic acid (AA). |
| Symbol |   GHS06,GHS09 |
| Signal word | Danger |
| Hazard statements | H301 - H410 |
| Precautionary statements | P273 - P301 + P310 + P330 |
| Hazard Codes | T,N |
| Risk Statements | 25-50 |
| Safety Statements | 45-61 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥90% (LC/MS-ELSD) |
| Storage Temp. | −20°C |
| UNSPSC | 12352205 |