Tephrosin
SIGMA/SMB00172 - ≥95% (LC/MS-ELSD)
Synonym: Deguelinol I; Hydroxydeguelin
CAS Number: 76-80-2
Empirical Formula (Hill Notation): C23H22O7
Molecular Weight: 410.42
MDL Number: MFCD00238693
Linear Formula: C23H22O7
Product Type: Chemical
assay | ≥95% (LC/MS-ELSD) |
form | solid |
InChI | 1S/C23H22O7/c1-22(2)8-7-1 |
InChI key | AQBZCCQCDWNNJQ-AUSIDOKSSA |
SMILES string | COc1cc2OC[C@H]3Oc4c(ccc5O |
storage temp. | −20°C |
Biochem/physiol Actions: | Tephrosin is a plant-based rotenoid which has known anti-cancer properties. Tephrosin inhibited proliferation in A549 cancer cells in a dose-sependent manner. Tephrosin has been shown to induce capase-independent apoptosis, and internalization and degradation of inactivated EGFR and ErB2 in human colon cancer cells. |
General description: | Natural product derived from plant source. |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H410 |
Precautionary statements | P273 - P501 |
Hazard Codes | N |
Risk Statements | 50 |
Safety Statements | 61 |
RIDADR | UN 3077 9 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% (LC/MS-ELSD) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |