3,4-Di-O-caffeoylquinic acid
SIGMA/SMB00224 - ≥90% (LC/MS-ELSD)
Synonym: 3,4-DICQA; 3,4-
CAS Number: 14534-61-3
Empirical Formula (Hill Notation): C25H24O12
Molecular Weight: 516.45
MDL Number: MFCD22375481
Linear Formula: C25H24O12
Product Type: Chemical
assay | ≥90% (LC/MS-ELSD) |
form | solid |
InChI | 1S/C25H24O12/c26-15-5-1-1 |
InChI key | UFCLZKMFXSILNL-PSEXTPKNSA |
Quality Level | 200 ![]() |
SMILES string | O[C@@H]1C[C@](O)(C[C@@H]( |
storage temp. | −20°C |
Application: | 3,4-Di-O-caffeoylquinic acid has been used as a reference standard: • to quantify the caffeoylquinic acids of Artemisia frigida Willd. (Fringed sagewort) using high-performance liquid chromatography with diode array detection and electrospray ionization triple quadrupole mass spectrometric detection (HPLC-DAD-ESI-QQQ-MS) • to quantify the phenolic compounds of Artemisia species using high-performance liquid chromatography with diode array detection (HPLC-DAD) technique • for metabolic profiling of methanolic leaf extract of A. nallamalayana and to identify the phenolic acids using High-Performance Liquid Chromatography-Ultraviole |
Biochem/physiol Actions: | 3,4-Di-O-caffeoylquinic acid, along with 3,5-dicaffeoylquinic acid and luteolin-7-O-glucoside, is a component of the medicinal herb Youngia japonica. It has known antiviral activity and along with 3,5,-dicaffeoylquinic acid, shows activity against respiratory syncyntial virus (RSV). 3,4-COQ elicits antioxidant effects which mediate its neuroprotective effects against in vitro retinal damage. It also exerts cytoprotective effects against oxidative damage in bone marrow-derived mesenchymal stem cells (bmMSCs). |
General description: | 3,4-Di-O-caffeoylquinic acid (3,4-COQ) is a component of the medicinal herb Youngia japonica.It has a caffeoyl moiety attached with a hexacyclic quinic acid in its structure. |
Packaging: | 1 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥90% (LC/MS-ELSD) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |