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Coptisine Chloride

SIGMA/SMB00314 - ≥98% (HPLC)

Synonym: Coptisine chloride; Bis(methylenedioxy)protoberberine chloride; Coptisin Chloride

CAS Number: 6020-18-4
Empirical Formula (Hill Notation): C19H14ClNO4
Molecular Weight: 355.77
MDL Number: MFCD00016676
Linear Formula: C19H14ClNO4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SMB00314-25MG 25 mg
 $0.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: SMB00314-100MG

 

application(s) metabolomics
vitamins, nutraceuticals, and natural products
assay ≥98% (HPLC)
form powder
InChI 1S/C19H14NO4.ClH/c1-2-16-19(24-10-21-16)14-8-20-4-3-12-6-17-18(23-9-22-17)7-13(12)15(20)5-11(1)14;/h1-2,5-8H,3-4,9-10H2;1H/q+1;/p-1
InChI key LUXPUVKJHVUJAV-UHFFFAOYSA-M
Quality Level 200 
SMILES string C1(OCO2)=C2C=C(CC[N+]3=C4C=C5C(C(OCO6)=C6C=C5)=C3)C4=C1.[Cl-]
storage temp. −20°C
Application: Coptisine Chloride has been used to study its binding interactions with single-stranded poly(A) using different absorbance and thermal melting spectroscopic experiments. It may have been used as a standard to analyze Chelidonium majus L. extracted compounds using UV/VIS absorption spectroscopy.
Biochem/physiol Actions: Coptisine Chloride is a potent anti-malarial compound, which also exerts anti-cancer and anti-diabetic properties. It elicits protective effects on gastric mucus membrane and is used as a traditional medicine against gastroenteric diseases. Coptisine chloride also displays anti-microbial activities.It has been analyzed as a cytotoxic agent in hepatoma and leukemic cells and is reported to block cell cycle progression.
General description: Coptisine chloride is a cytotoxic isoquinoline alkaloid. It is the major bioactive compound of Coptis rhizome, and can also be found in different plants such as Chelidonium majus, Enantia chlorantha. Coptisine is related to berberine and has a similar structure to that of Jatrorrhizine.
Packaging: 25, 100 mg in poly bottle
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352205

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