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Ginsenoside Compound K

SIGMA/SMB00348 - ≥96% (HPLC)

Synonym: (3B,12B)-3,12-Dihydroxydammar-24-en-20-yl β-D-glucopyranoside; 20(S)-Ginsenoside Ck; Ginsenoside K; Protopanaxadiol 20-O-glucoside

CAS Number: 39262-14-1
Empirical Formula (Hill Notation): C36H62O8
Molecular Weight: 622.87
Linear Formula: C36H62O8
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SMB00348-5MG 5 mg
$220.00
1/EA
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application(s) metabolomics
vitamins, nutraceuticals, and natural products
assay ≥96% (HPLC)
form powder
InChI 1S/C36H62O8/c1-20(2)10-9-14-36(8,44-31-30(42)29(41)28(40)23(19-37)43-31)21-11-16-35(7)27(21)22(38)18-25-33(5)15-13-26(39)32(3,4)24(33)12-17-34(25,35)6/h10,21-31,37-42H,9,11-19H2,1-8H3/t21?,22-,23-,24?,25?,26+,27?,28-,29+,30-,31+,33+,34-,35-,36+/m1/s1
InChI key FVIZARNDLVOMSU-KJULZEBLSA-N
Quality Level 200 
SMILES string CC(C)=CCC[C@](C1C2[C@H](O)CC3[C@@]([C@]2(C)CC1)(C)CCC4C(C)(C)[C@@H](O)CC[C@@]43C)(C)O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O
Application:

  • Combination of Electrochemistry and Mass Spectrometry to Study Nitric Oxide Metabolism and Its Modulation by Compound K in Breast Cancer Cells.: This research explores the interaction of Ginsenoside Compound K with nitric oxide metabolism in breast cancer cells, employing a combination of electrochemical techniques and mass spectrometry to elucidate the metabolic pathways and potential therapeutic effects of Compound K (Zhao et al., 2022 ).

  • Metabolic analysis of Panax notoginseng saponins with gut microbiota-mediated biotransformation by HPLC-DAD-Q-TOF-MS/MS.: This article investigates the gut microbiota-mediated biotransformation of Panax notoginseng saponins, including Compound K, detailing the complex interactions and metabolic profiles in a biological system, which could inform their therapeutic use and bioavailability (Chen et al., 2018 ).

Biochem/physiol Actions: Ginsenoside compound K has many pharmacological properties that include anti-diabetic, anti-inflammatory, hepatoprotective, anti-allergic, and anti-carcinogenic effects. It also displays neuroprotective properties, in mice it has shown recovery from synaptic loss and memory impairment. Ginsenoside K can inhibit several gene expressions in human umbilical vein endothelial cells (HUVECs), resulting in the inhibition of migration and angiogenesis of endothelial cells.
General description: Ginsenoside Compound K is a tetracyclic dammarane-type triterpenoid saponin found in the roots of Panax ginseng. It is a major constituent in ginseng, which has been traditionally used to increase resistance to stress and aging.
Packaging: 25 mg in poly bottle
Packaging: 5 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥96% (HPLC)
UNSPSC 12352205

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