2,4,3′,5′-tetramethoxystilbene

SIGMA/SMB00388 - ≥98% (HPLC)

Synonym: 2,4,3′,5′-tetramethoxystilbene; 1-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-2,4-dimethoxy-benzene; 2,3′,4,5′-Tetramethoxystilbene

CAS Number: 24144-92-1
Empirical Formula (Hill Notation): C₁₈H₂₀O₄
Molecular Weight: 300.35
MDL Number: MFCD03428621
Linear Formula: C₁₈H₂₀O₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SMB00388-10MG	10 mg	$173.00 1/EA	Add To Favorites

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This image depicts SKU: SMB00388-50MG

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to yellow
form	powder
InChI	1S/C18H20O4/c1-19-15-8-7-14(18(12-15)22-4)6-5-13-9-16(20-2)11-17(10-13)21-3/h5-12H,1-4H3/b6-5+
InChI key	JDBCWSHYEQUBLW-AATRIKPKSA-N
Quality Level	200
SMILES string	COC1=CC(OC)=CC=C1/C=C/C2=CC(OC)=CC(OC)=C2
storage temp.	−20°C
technique(s)	HPLC: suitable

Biochem/physiol Actions:	2,3′,4,5′-Tetramethoxystilbene, also known as TMS, is a selective and competitive inhibitor of cytochrome P450 1B. It is a synthetic trans-stilbene analog. TMS is an analog of resveratrol and is an anti-cancer agent. TMS is cytotoxic to gefitinib-resistant (G-R) non-small-cell lung cancer (NSCLC) cells. It binds to sarco/endoplasmic reticulum Ca²⁺-ATPase (SERCA) and promotes apoptosis and autophagy. TMS is also a selective inhibitor of CYP1B1.
Packaging:	10 mg in glass bottle
Packaging:	50 mg in poly bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	−20°C
UNSPSC	85151701

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