Platycodin D

SIGMA/SMB00424 - ≥98% (HPLC)

Synonym: 3β-(β-D-glucopyranosyloxy)-2β,16α,23,24-tetrahydroxy-O-D-apio-β-D-furanosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-olean-12-en-28-oic acid

CAS Number: 58479-68-8
Empirical Formula (Hill Notation): C₅₇H₉₂O₂₈
Molecular Weight: 1225.32
Linear Formula: C₅₇H₉₂O₂₈
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SMB00424-10MG	10 mg	$364.00 1/EA	Add To Favorites
45-SMB00424-50MG	50 mg	$0.00 1/EA CALL FOR PRICE	Add To Favorites

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This image depicts SKU: SMB00424-50MG

Properties
Descriptions
Safety Info.
Basic Data

application(s)	metabolomics vitamins, nutraceuticals, and natural products
assay	≥98% (HPLC)
form	powder
InChI	1S/C57H92O28/c1-23-40(81-45-39(72)41(30(64)18-76-45)82-49-43(73)56(75,21-61)22-78-49)36(69)38(71)46(79-23)83-42-33(66)29(63)17-77-48(42)85-50(74)57-12-11-51(2,3)14-27(57)24-7-9-52(4)26-13-28(62)44(84-47-37(70)35(68)34(67)31(16-58)80-47)55(19-59,20-60)25(26)8-10-54(52,6)53(24,5)15-32(57)65/h7,23,25-49,58-73,75H,8-22H2,1-6H3/t23-,25+,26-,27-,28-,29-,30+,31+,32+,33-,34+,35-,36-,37+,38+,39+,40-,41-,42+,43-,44-,45-,46-,47-,48?,49-,52+,53+,54+,56+,57+/m0/s1
InChI key	RJDYKSRQTBCKLC-XTIQGCOGSA-N
Quality Level	200
SMILES string	O[C@@H]1[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)C(CO)(CO)[C@]3([H])CC[C@@]4(C)[C@]5(C)C[C@@H](O)[C@@]6(C(O[C@H]7[C@H](O[C@@H]8O[C@@H](C)[C@H](O[C@H]9[C@H](O)[C@@H](O[C@@H]%10OC[C@@](CO)(O)[C@H]%10O)[C@H](O)CO9)[C@@H](O)[C@H]8O)[C@@H](O)[C@@H](O
storage temp.	2-8°C

Application:	Platycodin D has been used: • to test its anti-inflammatory and inhibitory effect on eosinophilic airway inflammation and T-helper type 2 (Th2) signaling pathways using ovalbumin (OVA)-induced allergic asthma mouse model • to test its anti-obese effects on the activation of brown adipose tissue featuring in vivo and in vitro studies • to test its efficacy as an adjuvant with infectious bronchitis (IB) vaccine in chicken
Biochem/physiol Actions:	Platycodin D elicits strong anti-cancer properties and exhibits cytotoxicity against several cancer cell lines of both in vitro and in vivo origin. It exerts anti-inflammatory and protective effects against lipopolysaccharide (LPS)-induced acute lung injury (ALI) by upregulating liver-X receptors α (LXRα) and ATP-binding cassette transporter A1 (ABCA1) signaling pathway. It also possesses protective effects against Cisplatin (CDDP)-induced nephrotoxicity in mice.
General description:	Platycodin D (PD) is a triterpenoid saponin found in the root of Platycodon grandifloras called Platycodonis Radix.
Packaging:	10 mg in glass bottle
Packaging:	50 mg in poly bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P301 + P312 + P330
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352205

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