Sophoricoside
SIGMA/SMB00438 - ≥98% (HPLC)
Synonym: 5′,7′-Dihydroxy-4′-glucosyloxyisoflavone; Genistein-4′-O-glucoside
CAS Number: 152-95-4
Empirical Formula (Hill Notation): C21H20O10
Molecular Weight: 432.38
Linear Formula: C21H20O10
Product Type: Chemical
assay | ≥98% (HPLC) |
form | powder |
InChI | 1S/C21H20O10/c22-7-15-18( |
InChI key | ISQRJFLLIDGZEP-JDCPMNFLSA |
Quality Level | 200 ![]() |
SMILES string | OC1=CC(O)=C(C(C(C2=CC=C(O |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Sophoricoside (SOP) improves lipopolysaccharides (LPS)-induced acute lung injury (ALI) in mice by activating the adenosine monophosphate-activated protein kinase (AMPK)/nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway. It also improves contact dermatitis by inhibiting the nuclear factor-kappa B (NF-κB) pathway in B cells in mice model. |
Biochem/physiol Actions: | Sophoricoside elicits anti-cancer, immunosuppressive, and anti-inflammatory activities. It inhibits proinflammatory cytokine production in human mast cells and has the potential to treat allergic inflammation diseases. |
General description: | Sophoricoside is an isoflavone glycoside found in the fruit of Sophora japonica. It is a structural isomer of genistin. |
Packaging: | 25 mg in poly bottle |
Packaging: | 5 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |