Sophoricoside

SIGMA/SMB00438 - ≥98% (HPLC)

Synonym: 5′,7′-Dihydroxy-4′-glucosyloxyisoflavone; Genistein-4′-O-glucoside

CAS Number: 152-95-4
Empirical Formula (Hill Notation): C₂₁H₂₀O₁₀
Molecular Weight: 432.38
Linear Formula: C₂₁H₂₀O₁₀
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SMB00438-25MG	25 mg	$507.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

application(s)	metabolomics vitamins, nutraceuticals, and natural products
assay	≥98% (HPLC)
form	powder
InChI	1S/C21H20O10/c22-7-15-18(26)19(27)20(28)21(31-15)30-11-3-1-9(2-4-11)12-8-29-14-6-10(23)5-13(24)16(14)17(12)25/h1-6,8,15,18-24,26-28H,7H2/t15-,18-,19+,20-,21-/m0/s1
InChI key	ISQRJFLLIDGZEP-JDCPMNFLSA-N
Quality Level	200
SMILES string	OC1=CC(O)=C(C(C(C2=CC=C(O[C@H]3O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]3O)C=C2)=CO4)=O)C4=C1
storage temp.	2-8°C

Biochem/physiol Actions:	Sophoricoside (SOP) improves lipopolysaccharides (LPS)-induced acute lung injury (ALI) in mice by activating the adenosine monophosphate-activated protein kinase (AMPK)/nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway. It also improves contact dermatitis by inhibiting the nuclear factor-kappa B (NF-κB) pathway in B cells in mice model.
Biochem/physiol Actions:	Sophoricoside elicits anti-cancer, immunosuppressive, and anti-inflammatory activities. It inhibits proinflammatory cytokine production in human mast cells and has the potential to treat allergic inflammation diseases.
General description:	Sophoricoside is an isoflavone glycoside found in the fruit of Sophora japonica. It is a structural isomer of genistin.
Packaging:	25 mg in poly bottle
Packaging:	5 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352205

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