Synonym: 5-[(1S,3aR,4R,6aR)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole
CAS Number: 526-07-8
Empirical Formula (Hill Notation): C20H18O7
Molecular Weight: 370.35
Linear Formula: C20H18O7
Product Type: Chemical
| assay |
≥97% |
| biological source |
Sesamum indicum (sesame) |
| form |
powder |
| InChI |
1S/C20H18O7/c1-3-15-17(25-9-23-15)5-11(1)19-13-7-22-20(14(13)8-21-19)27-12-2-4-16-18(6-12)26-10-24-16/h1-6,13-14,19-20H,7-10H2/t13-,14-,19+,20+/m0/s1 |
| InChI key |
ZZMNWJVJUKMZJY-AFHBHXEDSA-N |
| Quality Level |
200  |
| SMILES string |
[H][C@@]12[C@@H](C(C=C3)=CC4=C3OCO4)OC[C@]1([H])[C@@H](OC5=CC6=C(C=C5)OCO6)OC2 |
| solubility |
DMSO: 10 mg/mL |
| storage temp. |
−20°C |
| Biochem/physiol Actions: |
It also exerts antimicrobial, anti-melanogenesis, and neuroprotective effects. |
| Biochem/physiol Actions: |
Sesamolin is reported to have beneficial physiological properties such as antioxidant, anti-mutagenic, anti-aging and anti-inflammatory activities. It was also found to inhibit lipid peroxidation in rat liver and kidney. Sesamolin enhances NK cell lysis activity by increasing the expression of NKG2D ligands on Burkitt′s lymphoma cells, presenting a potential immunotherapeutic value for cancer treatment. In addition, it was demonstrated that sesamolin inhibits β-secretase, presenting an important role for prevention of dementia by daily consumption. |
| General description: |
Sesamolin is a furofuran lignan extracted from Sesamum indicum L. (sesame) seeds. Its solubility is very less in water. The chemical structure of sesamolin comprises two phenylpropanoids with their propyl side attached to a central carbon. It is reported in many other Sesamum species. |
| Symbol |
 GHS07 |
| Signal word |
Warning |
| Hazard statements |
H317 |
| Precautionary statements |
P280 - P302 + P352 |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥97% |
| Storage Temp. |
−20°C |
| UNSPSC |
12352200 |
