Sesamin
SIGMA/SMB00705 - ≥98% (HPLC)
Synonym: Fagarol; Fagarol
CAS Number: 607-80-7
Empirical Formula (Hill Notation): C20H18O6
Molecular Weight: 354.35
MDL Number: MFCD00216134
Linear Formula: C20H18O6
Product Type: Chemical
| application(s) | metabolomics vitamins, nutraceuticals, and natural products |
| assay | ≥98% (HPLC) |
| form | powder |
| InChI | 1S/C20H18O6/c1-3-15-17(25 |
| InChI key | PEYUIKBAABKQKQ-AFHBHXEDSA |
| Quality Level | 200 ![]() |
| SMILES string | C1Oc2ccc(cc2O1)[C@H]3OC[C |
| solubility | DMSO: 10 mg/mL |
| storage temp. | −20°C |
| Application: | Sesamin has been used as a reference standard to study the activity of Cytochrome P450 enzyme sesamin synthase from Sesamum indicum L. in the conversion of pinoresinol to sesamin. |
| Biochem/physiol Actions: | Non-competitive Δ5-desaturase inhibitor. |
| Biochem/physiol Actions: | Sesamin presents multiple health benefits including hypocholesterolemic, anti-hypertensive, anti-carcinogenic, anti-aging, immunoregulatory, hypoglycemic, anti-thrombotic, hepatoprotective, and antioxidant activities. It has also been demonstrated to work synergistically with vitamin E against lipid peroxidation. Sesamin was found to be metabolized into several catechol forms in the liver. These cathecols have a potent ability to scavenge superoxide radicals. |
| General description: | Sesamin is the most abundant lignan isolated from Sesamum indicum or sesame seeds and sesame oil. |
| Symbol | GHS07 |
| Signal word | Warning |
| Hazard statements | H317 |
| Precautionary statements | P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352205 |


