Lycopene
SIGMA/SMB00706 - ≥98% (HPLC), from tomato
Synonym: ψ,ψ-Carotene; 2,6,10,14,19,23,27,31-
CAS Number: 502-65-8
Empirical Formula (Hill Notation): C40H56
Molecular Weight: 536.87
MDL Number: MFCD00017350
Linear Formula: C40H56
Product Type: Chemical
| assay | ≥98% (HPLC) |
| form | powder |
| InChI | 1S/C40H56/c1-33(2)19-13-2 |
| InChI key | OAIJSZIZWZSQBC-GYZMGTAESA |
| Quality Level | 200  |
| shipped in | dry ice |
| SMILES string | CC(C)=CCCC(C)=CC=CC( |
| solubility | chloroform: 5 mg/mL |
| THF: 1 mg/mL | |
| storage condition | protect from light |
| storage temp. | −20°C |
| Application: | Lycopene has been used: • to analyze its chemo-preventive effects on cutaneous tumors in in vitro mouse epidermal cell line • as a reference standard for quantitative high-performance liquid chromatography (HPLC) to analyze antioxidant capacity of endogenous carotenoids in mammalian cell lines • as a reference standard in high-performance liquid chromatography (HPLC) to identify carotenoids from engineered Saccharomyces cerevisiae |
| Biochem/physiol Actions: | Antioxidant micronutrient of tomatoes associated with decreased risk for cancer and cardiovascular disease. Enhances gap juction communication between cells via upregulation of connexin 43 and reduces proliferation of cancer cells in culture. Inhibits cholesterol synthesis and enhances low-density lipoprotein degradation. |
| Biochem/physiol Actions: | Lycopene has been found to be active against oral cancer and to inhibit metastasis of human liver adenocarcinoma cells by down regulation of NOX4. Lycopene was also found to be a beneficial supplement for people with cardiovascular diseases. |
| General description: | Lycopene is a carotenoid found in many red fruits and vegetables such as watermelon, pink guava, and tomato. Lycopene is a potent antioxidant. It is suggested that lycopene is used by the plant to protect against reactive oxygen species (ROS). |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |