Synonym: (S)-(+)-Clopidogrel bisulfate; (S)-(+)-Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrogensulfate; Clopidogrel Bisulphate
CAS Number: 120202-66-6
Empirical Formula (Hill Notation): C16H16ClNO2S · H2SO4
Molecular Weight: 419.90
MDL Number: MFCD00876395
Linear Formula: C16H16ClNO2S · H2SO4
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
white to tan |
| form |
powder |
| InChI |
1S/C16H16ClNO2S.H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14;1-5(2,3)4/h2-5,7,9,15H,6,8,10H2,1H3;(H2,1,2,3,4)/t15-;/m0./s1 |
| InChI key |
FDEODCTUSIWGLK-RSAXXLAASA-N |
| optical activity |
[α]/D +54 to +70°, c = 0.5 in methanol |
| originator |
Bristol-Myers Squibb |
| |
Sanofi Aventis |
| Quality Level |
100  |
| SMILES string |
OS(O)(=O)=O.COC(=O)[C@@H](N1CCc2sccc2C1)c3ccccc3Cl |
| solubility |
DMSO: ≥20 mg/mL (warmed) |
| storage temp. |
2-8°C |
| Application: |
(S)-(+)-Clopidogrel hydrogensulfate was used as standard in HPLC-MS/MS to detect clopidogrel and its thiol derivative in human plasma. |
| Biochem/physiol Actions: |
(S)-(+)-Clopidogrel hydrogen sulfate is an antithrombotic antiplatelet agent. |
| Biochem/physiol Actions: |
(S)-(+)-Clopidogrel hydrogen sulfate is an antithrombotic antiplatelet agent. It specifically and irreversibly inhibits the Purinoceptor P2Y12 subtype which inhibits ADP-induced platelet aggregation. (S)-(+)-Clopidogrel hydrogen sulfate is the active isomer. |
| Features and Benefits: |
This compound is featured on the P2 Receptors: P2Y G-Protein Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Features and Benefits: |
This compound was developed by Bristol-Myers Squibb and Sanofi Aventis . To browse the list of other pharma-developed compounds, Approved Drugs, and Drug Candidates, click here . |
| Packaging: |
10, 50 mg in glass bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |
