CK-666
SIGMA/SML0006 - ≥98% (HPLC), powder
Synonym: 2-
CAS Number: 442633-00-3
Empirical Formula (Hill Notation): C18H17FN2O
Molecular Weight: 296.34
MDL Number: MFCD03036271
Linear Formula: C18H17FN2O
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white to tan |
| form | powder |
| InChI | 1S/C18H17FN2O/c1-12-13(14 |
| InChI key | UXRKUKRXVWJFER-UHFFFAOYSA |
| Quality Level | 100 ![]() |
| SMILES string | Cc1[nH]c2ccccc2c1CCNC(=O) |
| solubility | DMSO: ≥25 mg/mL |
| storage temp. | 2-8°C |
| Application: | CK-666 may be used to study Arp2/3-mediated structural changes in cells. |
| Biochem/physiol Actions: | CK-666 binds to Arp2/3 complex, stabilizes the inactive state of the complex and prevents its movement into active conformation. |
| Biochem/physiol Actions: | CK-666 is a cell-permeable inhibitor of actin assembly mediated by actin-related protein Arp2/3 complex. |
| Packaging: | 5, 25 mg in glass bottle |
| Hazard Codes | Xi |
| Risk Statements | 36 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |

