VAHA
SIGMA/SML0011 - ≥98% (HPLC)
Synonym: VAHA; Valproyl hydroxamic acid, VPA-HA
CAS Number: 106132-78-9
Empirical Formula (Hill Notation): C8H17NO2
Molecular Weight: 159.23
MDL Number: MFCD12756348
Linear Formula: C8H17NO2
Product Type: Chemical
| assay | ≥98% (HPLC) |
| form | powder |
| InChI | 1S/C8H17NO2/c1-3-5-7(6-4- |
| InChI key | ROJGIRXXBBBMPL-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | CCCC(CCC)C(=O)NO |
| solubility | DMSO: ≥25 mg/mL |
| storage temp. | 2-8°C |
| Application: | VAHA may be used in cell signaling studies. |
| Biochem/physiol Actions: | Hydroxamic acid derivatives of valproic acid exhibit anticonvulsant activity with no teratogenic activity in mouse neural tube defect model. It is effective in the treatment of bipolar disorders. |
| Biochem/physiol Actions: | VAHA (Valproyl hydroxamic acid) is an HDAC inhibitor with less activity than valproic acid against Class I enzymes but much greater Class II activity |
| Biochem/physiol Actions: | VAHA is an HDAC inhibitor |
| Features and Benefits: | This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
| Packaging: | 5, 25 mg in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |