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Scutellarin hydrate

SIGMA/SML0014 - ≥98% (HPLC)

Synonym: 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-ß-D-glucopyranosiduronic acid hydrate; 7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one hydrate; Breviscapin; Scutellarein-7-O-β-D-glucuronide

CAS Number: 27740-01-8
Empirical Formula (Hill Notation): C21H18O12 · xH2O
Molecular Weight: 462.36 (anhydrous basis)
Linear Formula: C21H18O12 · xH2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0014-5MG 5 mg
 $107.00
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This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

assay ≥98% (HPLC)
color yellow
form powder
InChI 1S/C21H18O12/c22-8-3-1-7(2-4-8)10-5-9(23)13-11(31-10)6-12(14(24)15(13)25)32-21-18(28)16(26)17(27)19(33-21)20(29)30/h1-6,16-19,21-22,24-28H,(H,29,30)/t16-,17-,18+,19-,21+/m0/s1
InChI key DJSISFGPUUYILV-ZFORQUDYSA-N
Quality Level 100 
SMILES string O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1C(=O)O)O)O)O)Oc2cc3c(c(c2O)O)C(=O)C=C(O3)c4ccc(cc4)O
solubility DMSO: ≥10 mg/mL
storage condition desiccated
storage temp. 2-8°C
Application: Scutellarin hydrate may be used in MAPK-mediated cell signaling studies.
Biochem/physiol Actions: Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion model, the compound reduced infarct volume and neurological deficits by increasing eNOS expression while inhibiting the induction of iNOS.
Features and Benefits: This compound is featured on the MAPKs  and Nitric Oxide Synthases  pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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