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Itopride hydrochloride

SIGMA/SML0033 - ≥98% (HPLC)

Synonym: N-[[4-[2-(Dimethylamino)ethoxy]phenyl]methyl]-3,4-dimethoxy benzamidehydrochloride; N-[p-[2-(dimethylamino)ethoxy]benzyl]veratramide hydrochloride

CAS Number: 122892-31-3
Empirical Formula (Hill Notation): C20H26N2O4 ·HCl
Molecular Weight: 394.89
MDL Number: MFCD00881710
Linear Formula: C20H26N2O4 ·HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML0033-10MG 10 mg
 $128.00
1/EA		 Add To Favorites
45-SML0033-50MG 50 mg
 $506.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to tan
form powder
InChI 1S/C20H26N2O4.ClH/c1-22(2)11-12-26-17-8-5-15(6-9-17)14-21-20(23)16-7-10-18(24-3)19(13-16)25-4;/h5-10,13H,11-12,14H2,1-4H3,(H,21,23);1H
InChI key ZTOUXLLIPWWHSR-UHFFFAOYSA-N
originator Abbott
Quality Level 100 
SMILES string Cl.COc1ccc(cc1OC)C(=O)NCc2ccc(OCCN(C)C)cc2
solubility H2O: ≥48 mg/mL
storage condition desiccated
storage temp. 2-8°C
Biochem/physiol Actions: Antagonist of dopamine D2-receptor with anticholinesterase activity.
Biochem/physiol Actions: Itopride hydrochloride enhances the gastrointestinal motility by blocking the activity of dopamine on the D2 receptors, on the post-synaptic cholinergic nerves and by inducing the liberation of acetylcholine in the myenteric plexus. It also inhibits the hydrolysis of the released acetylcholine with the help of acetylcholinesterase.
Biochem/physiol Actions: Itopride is an acetylcholinesterase (AChE) inhibitor and D2 dopamine receptor antagonist. Itopride is used as a gastroprokinetic agent.
Features and Benefits: This compound was developed by Abbott . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
General description: Itopride hydrochloride is a new prokinetic drug.
Packaging: 10, 50 mg in glass bottle
Symbol GHS09  GHS09
Signal word Warning
Hazard statements H410
Precautionary statements P273 - P501
Hazard Codes N
Risk Statements 50
Safety Statements 61
RIDADR UN 3077 9 / PGIII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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