1-EBIO
SIGMA/SML0034 - ≥98% (HPLC)
Synonym: 1-
CAS Number: 10045-45-1
Empirical Formula (Hill Notation): C9H10N2O
Molecular Weight: 162.19
EC Number: 233-148-1
MDL Number: MFCD00005715
Linear Formula: C9H10N2O
Product Type: Chemical
| assay | ≥98% (HPLC) |
| form | powder |
| InChI | 1S/C9H10N2O/c1-2-11-8-6-4 |
| InChI key | CXUCKELNYMZTRT-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | CCN1C(=O)Nc2ccccc12 |
| solubility | DMSO: ≥20 mg/mL |
| storage temp. | room temp |
| Application: | 1-EBIO was used to study the electrical activity modulated by Ca+2-activated K+ channels in rat central neurons. The effect of 1-EBIO on human intermediate conductance channels was studied. |
| Biochem/physiol Actions: | 1-EBIO is an activator of epithelial Ca2+-activated K+ channel also known as the intermediate-conductance Ca(2+)-activated K(+) channel (IK-1) or KCa3.1. |
| Biochem/physiol Actions: | 1-EBIO is an activator of epithelial Ca2+-activated K+ channel |
| Biochem/physiol Actions: | 1-EBIO potentiates the secretion of CFTR-mediated Cl− ion secretion by activating the basolateral KCNN4 K+ channels in native human colonic tissues. It stimulates the apical Cl− channels and Ca+2-dependent basolateral K+ channels to stimulate fluid transport in lacrimal glands. |
| Packaging: | 10, 50 mg in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 - H319 |
| Precautionary statements | P301 + P312 + P330 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-36 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | room temp |
| UNSPSC | 12352200 |